马拉色菌的研究进展

Study Progress of Malassezia

马拉色菌是一种嗜脂的酵母菌,亦是一种条件性致病菌。目前,分为7种类型。据报道在形态学、生理、生化及培养基等方面有其独特的生物学特性。马拉色菌能像酯酶一样分解脂质,而且可引起角质形成细胞形态学改变和细胞凋亡,这些都是它的主要致病因素。大量研究表明,马拉色菌可引起花斑癣、脂溢性皮炎、糠秕孢子菌毛囊炎和银屑病等,对于这些疾病的治疗可加用抗真菌药物。

Malassezia is a kind of yeast fungus with lipophilic character, and also a kind of conditional pathogenic bacteria. It is divided into 7 types at present. They had their specific bionomics in morphology, physiology, biochemistry, and culture medium. Malassezia can breakdown lipid like esterase, and result in morphological changes of malpighian cell and cell apoptosis, these are all their main etiological factors. Many reports suggested that Malassezia could cause Pityriasis Versicolor, Seborrbeic Dermatitis, Malassezia furfur FoUiculitis and Psoriasis et al. These can be cured by anti-fungus medicine.