4089例性病门诊患者沙眼衣原体检测结果分析

Detection of Chlamydia trachomatis in 4089 patients from STD clinic

目的：了解性病门诊患者沙眼衣原体感染情况。方法：用Microtrak Ⅱ EIA酶免法对自2004年4月～2005年12月收集的4089份男性尿道拭子和女性宫颈标本进行了沙眼衣原体抗原检测和革兰氏染色镜检炎症细胞。结果：共检出576份阳性标本，总检出率14.09％，其中男475份、女101份，男女性分别为15．66％和9．57％。炎症细胞检测发现男性无炎症感染率为50．74％（241／475），女性无炎症感染率48．51％（49／101）。不同年龄组沙眼衣原体感染率分别为20～29岁14．83％、30～39岁15．86％、40岁以上8．19％，以青壮年为主。20～29岁组与30～39岁组感染率差异无统计学意义（x^2=0．68，P〉0．05），而两组与40岁以上组感染率差异均有统计学意义（x^2=19．88，P〈0．01；x^2=25．27，P〈0.01）。结论：加强对高危人群尤其是无症状感染者筛查和检测，可有效控制泌尿生殖道沙眼衣原体的传播。

Objective：To investigate Chlamydia trachomatis infection among patients of STD clinic. Methods：A total of 4089 samples from male urogential tract and female endocervix were collected during Apr, 2004 to Dec, 2005 and detected for the antigen of Chlamydia trachomatis by Microtrak Ⅱ EIA and for pus cells by microscopy. Results：Out of 576 positive samples, 475 were from male patients and 101 from female. The overall infection rate was 14.09%, and it was 15.66% for male and 9. 57% for female. Among the patients with Chlamydia infection, 50. 74% （241/475） males and 48.51% （49/101）females did not show any signs of inflammation. The infection rate was 14. 83% in group aged 20 - 29 years, 15.86% in group aged 30 - 39 years and 8. 19% in group aged over 40, the young and middle - aged groups are predominant groups for Chlamydia infection. There was no significant difference of infection rates between the group aged 20 - 29 and 30 - 39 years （ P 〉 0. 05 ）, however, the infection rate of the two groups was significant higher than that in group over 40 （P 〈0. 01 ）. Conclusion：For control the spread of Chlamydia infection, it is important to screen and detect Chlamydia trachomatis＇ among the high risk people.