新生儿抗生素相关性腹泻的临床研究

Clinical Research of Antibiotic-Associated Diarrhea in the Newborns

目的探讨新生儿医院抗生素相关性腹泻(AAD)发病率、相关因素及临床特点,提出预防控制措施。方法对合并抗生素相关性腹泻的临床资料进行回顾性分析。结果住院新生儿AAD发生率为17.4%。AAD与新生儿胎龄、出生体重、日龄、联合用药数量、住院时间、医疗干预措施有关。结论合理使用抗生素,严格控制广谱抗生素的使用,减少侵袭性操作,是预防控制医院感染AAD的关键措施。

Objective To investigate the incidence, the characteristics, relative factors of antibiotic associated diarrhea （AAD） in the newborns and make measures to prevent and control it. Methods To study the data of antibiotic associated diarrhea. Results Incidence ratio of ADD was 17.4%, the risk of ADD related to the kinds of using compound antibiotics and period of treatment, using many meddling measures for medical and age. Conclusions Rational use of antibiotic, control use of antibiotic and reducing the state of consciousness were the key measures to prevent and control the AAD in nosocomial infection.