摘要
目的探讨联合检测CA125与CA153对诊断子宫内膜癌的临床价值。方法回顾性选择2005年1月至2006年9月在本院术前与术后均诊断为子宫内膜癌的病例48例,进行CA125与CA153联合检测,并在术后2～3个月进行复测;选取同期手术,经病理学检查证实为子宫肌瘤的病例96例为对照组。结果CA125和CA153两项指标联合检测较单项检测对辅助诊断子宫内膜癌的敏感性提高85.6%,但特异性有所下降,总准确率提高到80.5%,与对照组比较,差异有显著意义(P<0.05)。结论CA125和CA153两项肿瘤标志物联合检测,可提高子宫良性与恶性病变的鉴别能力,对判断疾病预后及复发有一定的参考意义。
Objective To evaluate the clinical value of combined detection of CA125 and CA153 for diagnosis of endometrial carcinoma. Methods The combined detection of CA125 and CA153 were performed in 48 inpatients with endometrial carcinoma who were suspected before surgery and being final diagnosed by pathological examinations after surgery, and 2 or 3 months after the operation. 96 cases of benign uterine myoma admitted for hysterectomy in the same period were control group. Results The sensitivity of combined detection of CA125 and CA153 for diagnosing endometrial carcinoma increased to 85.6 % and the specificity decreased subtly, Total accuracy rate of diagnosis reached 80.5%. There was statistical difference between the group of endometrial carcinoma and the control group（P〈0. 05）. Conclusion The combined detection of CA125 and CA153 has the important diagnostic value for differentiating benign and malignant diseases of uterus, The two markers can also predict the prognosis and recurrence of the carcinoma.
出处
《中华妇幼临床医学杂志（电子版）》
CAS
2008年第1期33-34,共2页
Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition)
