佛山市1899例健康体检者腰椎及左侧髋部骨密度测定结果分析

To analyse the bone mineral density of anteroposterior lumbar and left hip in 18 99 cases of physical examination

目的了解佛山市正常人群腰椎及左侧髋部骨密度（BMD）变化规律,探讨不同地区根据机型不同确定骨密度峰值（PBMD）的临床意义。方法利用Hologic公司DELPHI型双能X线骨密度仪（DEXA）测量佛山市1899例健康体检者的正位椎体及左侧髋部BMD,分性别、以5岁为1个年龄段对测量结果分层进行统计学分析,确定PBMD及标准差（SD）,并与由厂家提供的亚洲标准数据库正常参考值对照。结果佛山市男性和女性正位腰椎（L1-4）、左侧股骨颈（Neck）、左侧股骨粗隆（Troch）、左侧沃氏区（Wards）PBMD值分别为0.988、0.996、0.833、0.806、0.727、0.712、0.780和0.768g/cm^2。除男性正位腰椎和沃氏区PBMD出现在25～29岁年龄段外,其余PBMD均出现在30～34岁年龄段。除男性沃氏区和女性股骨粗隆PBMD与机内提供的正常参考值无统计学差异（P值分别为0.832、0.504）外,其他区域PBMD明显低于机内提供的正常参考值（P〈0.01）。结论佛山市腰椎及左侧髋部各区域PBMD年龄段与国内其他地区基本一致,但标准亚洲人数据库提供的PBMD参考值不适合DELPHI型DEXA评价该地区人群骨骼健康状况。

Objective To study the regularities of change in bone mineral density （BMD） of lumbar and hip and explore the importance of peak BMD（PBMD） in various regions and with different machines. Methods The BMD of anteroposterior （AP） lumbar （L1-4） and left hip were measured by Hologic DELPHI dual enengy X-ray absorptiometry （DEXA） for 1899 cases of physical examination （1010 males and 889 females, aged 21-78 years） in Foshan. The local PBMD and standard difference （SD） were obtained by stratified cluster sampling method and compared with that in Asian population normative data supplied by Hologic Co.. Results The location PBMD of AP L1-4 in 25-29 age group for males and 30-34 for females, were 0.988 （g/cm^2） and 0.996 （g/cm^2）, respectively. The PBMD of Neck and Troch in 30-34 age group both sexes, were 0.833（g/cm^2） and 0.727（g/ cm^2 ） for males and 0.806（g/cm^2 ） and 0.712（g/cm^2 ） for females. The PBMD of Ward＇s were 0.780（g/cm^2 ） and 0.768（g/cm^2 ）, occurred in 25-29 age for males and 30-34 age for females, respectively. Excepting PBMD of Ward＇s in males and Troch in females, they were significantly lower than in Asian population normative data （ P 〈 0.01 ）. Conclusions The regularities of change in BMD of lumbar and hip in Foshan accords with other mainland Chinese. Establishment of the PBMD reference value is important for various machines.