针灸治疗老年性痴呆的Meta-分析

Meta-analysis on acupuncture for treatment of dementia

目的:评价针刺治疗老年性痴呆的疗效。方法:按照循证医学(EBM)的要求全面检索了国内相关医学文献数据库近10年来的有关针灸治疗痴呆的文献,对纳入文献进行Meta-分析。结果:共纳入随机对照试验22篇,对其中19篇文献进行了Meta-分析。合并OR=3.72[2.73,5.07],漏斗图基本对称,提示针刺组对痴呆的治疗效果优于对照组(Z=8.32,P<0.00001)。结论:从国内的临床文献来看,针灸治疗痴呆有效,但试验研究质量有待进一步完善和提高。

Objective To assess the therapeutic effect of acupuncture on dementia. Methods The literatures of acupuncture for treatment of dementia are comprehensively searched in according with the demands of the evidencebased medicine （EBM）, which are collected from relevant domestic medical literature databases in the last ten years. Meta-analysis is conducted on the literatures enrolled. Results Twenty-two randomized controlled trials are included, among them, 19 trials are carried out by Meta-analysis. The total OR is 3.72[2.73, 5.07], and the funnel plot is approximately symmetry. It is indicated that the curative effect of acupuncture groups is better than the control groups （Z=8.32, P〈0. 000 01）. Conclusion Acupuncture therapy is effective on dementia according to the domestic clinical literatures. However, the quality of the studies needs further improving and increasing.