2-氯-5-甲基吡啶的侧链氯化

SIDE CHAIN CHLORINATION OF 2 CHLORO 5 METHYLPYRIDINE

研究影响２－氯－５－甲基吡啶的侧链氯化的主要因素发现，硫酰氯（ＳＯ２Ｃｌ２）是较理想的氯化剂，使用该氯化剂对２－氯－５－甲基吡啶的侧链氯化选择性较高，反应时间短，产物纯度高，反应步骤少。

chloro 5 chloromethylpyridine was prepared from the reaction of 2 chloro 5 methylpyridine with sulfonyl chloride, the preferred synthetic condition was given by studying the factors affecting the reaction.It is a noble method for synthesizing the compound.