摘要
用加不同浓度石棉纤维培养的AM上清液活化WI－38细胞，再加抗TNF抗体或IFN－γ，分别用3H-胸腺嘧啶（3H－TdR）和14C-脯氨酸（14C－Pro）掺入法，观察对肺成纤维细胞的作用。结果显示，抗TNF抗体，IFN－γ都有抑制成纤维细胞增殖的作用，并影响胶原合成。
Incubate WL-38 cells with AM supernatants induced by various amount of asbestos and antitumour necrosis antibody and interferon-gamma. The proliferation and collagen synthesis of fibroblast were measured by M-thymidine and 14 C-pro1ine incorporation respectively. The resultsdemonstrate that both anti-tumour necrosis antibody and interferon-gamma can inhibite the proliferation of fibroblast and decrease the collagen synthesis.
出处
《工业卫生与职业病》
CAS
CSCD
1997年第4期223-225,共3页
Industrial Health and Occupational Diseases
基金
江苏省卫生厅资助
