摘要
本实验研究了胆固醇对红景天苷脂质体的作用,重点考查了包封率、Zeta电位、粒径大小、渗漏率和丙二醛(malondialdehyde,MDA)含量等指标。结果表明,红景天苷脂质体的包封率随着胆固醇嵌入量的增加呈现先增加后减小的趋势,但胆固醇的嵌入量对载量影响不大。4℃和30℃下贮藏一个月,没有任何胆固醇嵌入的脂质体渗漏率达到10%和15%,随着胆固醇嵌入量增加至1:5和1:2,脂质体的渗漏率分别下降为6%、5%和12%、10%。进一步增大胆固醇的嵌入量至1:1,其渗漏率又会明显增加。胆固醇和卵磷脂脂质量比1:2时,脂质体在4℃、30℃下贮藏一个月的物理稳定性最好。
The effects of cholesterol on physicocbemical characteristics of salidroside containing liposomes were investigated in present work. The results showed that the higher the cholesterol content is, the higher the encapsulating efficiency of liposomes until its mass is equal to that of lecithin. However, cholesterol content shows little effect on the salidroside loading. Experimental data indicated that the leakage percentage of no cholesterol-liposomes reach 10% and 15% at 4℃ and 30 ℃ respetively during one month period, in comparison with the liposomes incorporating cholesterol （1：5 and 1：2, W/W） with 6%, 5% and 12%, 10%, respectively. Liposomes incorporating cholesterol （1：1, W/W） resulted in the increasing leakage again. In conclusion, liposomes incorporating cholesterol （1：2, W/W） can show a better performance.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2008年第2期59-63,共5页
Food Science
