短期接触O_3的小白鼠灌胃白果提取液对肝脏SOD活性的影响

Effect of O 3 and gingko solution on hepatic superoxide dismutase(SOD) activity in mice.

取体重１５～２０ｇ雄性小白鼠，随机分为四组：白果组、白果＋Ｏ３组、Ｏ３组、对照组，每组１０只。白果组每天灌胃白果提取液１０ｍｌ／ｋｇ；白果＋Ｏ３组除每天灌胃白果提取液外，隔天放入Ｏ３染毒柜中；Ｏ３组每天灌胃生理盐水１０ｍｌ／ｋｇ，并隔天放入Ｏ３染毒柜中；对照组在室内自由取食饮水。２０天后处死小白鼠取肝脏测定超氧化物歧化酶活性，结果表明，Ｏ３组肝脏ＳＯＤ活性明显高于对照组（Ｐ＜０．０５），其它各组之间无显著性差异。

40 male mices were divided randomly into 4 groups of 10 each,the 1st gingko group,the 2nd gingko+ O 3 group,the 3rd O 3 group,the 4th control group.For the 1st group,mice were given gingko solution orally 10ml/kg per day.The 2nd group∶mice were given gingko solution orally 10ml/kg per day and were put in O 3 chamber every other day.The 3rd group∶mice were given physiological saline orally 10ml/kg per day and were put in O 3 chamber every other day.The 4th group∶mice had taken food and water freely in normal condition.After 20 days,SOD activity was determined on liver in 40 sacrified mice.The results showed that SOD activity on liver in O 3 group was remarkable higher than that of control group( P <0.05),whereas no remarkable changes among other groups.