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食管癌患者手术前后血清可溶性白细胞介素-2受体动态观察 被引量:1

The detection and significance on the level of sIL 2R in patients with esophageal carcinoma before and after operation
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摘要 为探讨食管癌患者手术前后细胞免疫功能的变化,采用双抗体夹心ELISA法检测了54例食管癌患者手术前后血清sIL-2R水平,结果表明:sIL-2R显著高于正常人,且随肿瘤分期增加而增高。手术治疗1个月、3个月后,sIL-2R均有明显下降,但有转移的患者降低不明显。术后1周sIL-2R变化不明显,可能与机体的应激反应有关。提示血清sIL-2R可作为食管癌患者免疫功能的监测指标之一。对疾病的临床分期、疗效和预后的判断也有一定的帮助。 The serum level of sIL 2R in 54 patients with esophageal carcinoma were determined. The results showed that serum level of sIL 2R in patients was significantly higher than that of normal controls, and correlated with TNM stage of the disease. Forthermore, sIL 2R level was markedly decreased three months after operation ( P <0 01), but there were not much changes in metastatic patients ( P >0 05). The results suggest that serum sIL 2R may reflect the status of anti tumor immunity and prognosis of patients with esophageal carcinoma.
出处 《安徽医科大学学报》 CAS 1997年第3期200-202,共3页 Acta Universitatis Medicinalis Anhui
关键词 食管肿瘤 围手术期 SIL-2R 免疫学 eSH\ esophageal neoplasms/surgery esophageaneoplasms/immunol receptors, interleukin 2/blood
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