庚型肝炎病毒感染状况研究

A study on hepatitis G infection virus in children with viral hepatitis

为了解小儿庚型肝炎病毒（ＨＧＶ）感染状况，对５０６例各型病毒性肝炎患儿，采用以ＨＧＶ合成肽为抗原的酶联免疫吸附技术（ＥＬＩＳＡ）检测抗ＨＧＶ。结果表明，ＨＧＶ在小儿组感染率为４．０％。小儿组甲、乙、丙型肝炎中ＨＧＶ感染率分别为１．５％、５．４％和１．６％。其中乙型肝炎中感染率高于其他型（Ｐ＜０．０５）。抗ＨＧＶ在急性肝炎的检出率为１．５％，慢性肝炎中为４．８％。提示ＨＧＶ感染在小儿肝炎中占有一定比例，并有其特点。

The authors understand the condition of hepatitis G virus (HGV) infection in children, we detected anti HGV antibody by enzyme linked immunosorbent assay (ELISA) with HGV synthetic peptides as antigen in 506 children with viral hepatitis. The results showed that the prevalence rate of HGV infection in the 506 children was 4.0%, and was 1.5%, 5.4% and 1.6%, respectively, in children with hepatitis A,B and C, in which the prevalence rate of hepatitis B prodominated ( P <0.05). The positive rate of anti HGV in acute and chronic hepatitis was 1.5% and 4.8%, respectively. In conclusion, Attention should be paid to study on HGV infection prevalence and on its characteristics in children.