1978～1996年广州地区呼吸道合胞病毒感染分析

Respiratory syncytial virus infection in Guangzhou area from 1978 to 1996

为了解广州地区儿童呼吸道合胞病毒（ＲＳＶ）感染的情况，采用病毒分离等方法，对广州地区１９７８～１９９６年连续１８年的儿童支气管炎和支气管肺炎进行了ＲＳＶ病原学检测。共检测患儿５２７３例，分离出ＲＳＶ的患儿５１３例。病毒分离总阳性率９．７％。１８年中以１９８５年、１９８６年和１９９２年ＲＳＶ分离率最高；一年中ＲＳＶ分离率从３月份开始增高，４月份达高峰，持续至５～８月，９月份开始下降。结论：１８年来广州地区有过３次ＲＳＶ感染流行高峰（１９８５年、１９８６年、１９９２年）；广州地区ＲＳＶ感染的流行季节主要发生在每年的春夏季。

To study the prevalence of respiratory syncytial virus (RSV) infections in children, we employed the virus isolation methods to study the etiology of bronchitis and pneumonia of children in Guangzhou area from 1978 to 1996. RSV was isolated in 513 cases from 5 273 children with bronchitis and pneumonia. Total positive rate of RSV isolation was 9.7% with its peaks in 1985, 1986 and 1992, begining in March, peaking in April, lasting until May～August and declining in September in a year. In conclusion, there were three major RSV epidemics (1985, 1986, 1992) in Guangzhou area in the past 18 years. The epidemics of RSV infection mainly occurred from March to August in Guangzhou area every year.