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老年脑梗死患者血尿酸水平与凝血功能的相关性研究 被引量:6

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摘要 目的探讨老年脑梗死患者血尿酸水平升高与其凝血功能紊乱之间的相关性。方法采用临床前瞻性研究方法,将88例老年患者分为脑梗死组和非脑梗死组(对照组),比较两组患者的血尿酸和凝血功能检测值,分析血尿酸升高与凝血功能紊乱的关联性。结果脑梗死组血尿酸水平升高,患者的凝血功能发生促进脑梗死发病的相应改变,与对照组比较有显著性差异(P<0.05)。结论老年脑梗死患者血尿酸水平与其凝血功能密切相关。
作者 王绪芸
机构地区 烟台毓璜顶医院
出处 《中国老年学杂志》 CAS CSCD 北大核心 2008年第3期284-285,共2页 Chinese Journal of Gerontology
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  • 1Lehto S,Niskanen L,Ronnemaa T,et al. Serum uric acid is a strong predictor of stroke in patients with non-insulin-dependent diabetes mellitus[J]. Stroke,1998 ;29(3) :635-9.
  • 2Masuo K, Kawaguchi H, Mikami H, et al. Serum uric acid and plasma norepinephrlne concentrations predict subsequent weight gain and blood pressure elevation[J]. Hypertension, 2003 ;42 ( 4 ) :474-80.
  • 3各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33041
  • 4Vigna GB,Bolzan M,Romagnoni F,et al. Lipids and other risk factors selected by determinant analysis in symptomatic patients with supraaortic and peripheral atherosclerosis[J]. Circulation, 1992 , 85 : 200 -5.
  • 5Anker SD, Doehner W, Rauchhans M,et al. Uric acid and survival in chronic heart failure :validation and application in metabolic, functional, and hemodynamic staging [J]. Circulation,2003 ; 107 ( 15 ) : 1991-7.
  • 6Weir C J, Muir SW, Waiters MR, et al. Serum urate as an independent predictor of poor outcome and future vascular events after acute stroke[J]. Stroke,2003 ;34(8) :1951-6.
  • 7Foresti R, Sarathchandra P, Clark J-E, et al. Peroxynitrite induces haem oxygenase-1 in vascular endothelial cells:a link to apoptosis [J]. Biochem J,1999 ;339 ( Pt 3 ) :729-36.
  • 8Kean RB, Spitsin SV, Mikheeva T,et al. The peroxynitrite scavenger uric acid prevents inflammatory cell invasion into the central nervous system in experimental allergic encephalomyelitis though maintenance of blood- central nerous system barrier interity[J]. J Immunol,2000 ; 165:6511-8.
  • 9Catinella S,Pelizzi N,Marsilio R,et al. Determination of pufine compounds in carotid artery plaque by liquid chromatography electrospray ionization tandem mass spertrometry[J]. J Mass Spectrom,2001 ;36:441-2.
  • 10Furie B, Furie BC. P-Selectin induction of tissue factor biosynthesis and expression[J]. Haemostasis, 1996 ;26 ( suppl 1 ) :60.

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