白内障术前结膜囊细菌培养的病原学分析

Etiological analysis of the cosnjunctival bacterial flora before cataract sugery

目的分析近年来我院白内障手术前结膜囊细菌的构成和对药物敏感情况的变化。方法对1964眼白内障手术前结膜囊细菌培养结果和药物敏感实验结果进行分析。结果白内障患者手术前结膜囊细菌培养的阳性率为45.5%,主要是革兰氏阳性球菌,占98.32%。以表皮葡萄球菌(64.7%)和金黄色葡萄球菌(20.2%)为主。92.2%的结膜囊革兰氏阳性球菌对红霉素和青霉素耐药;大多数菌株对妥布霉素、万古霉素、环丙沙星和庆大霉素敏感;对妥布霉素和环丙沙星耐药有上升趋势。结论白内障手术前结膜囊细菌主要由表皮葡萄球菌构成,对红霉素和青霉素耐药;大多数菌株对妥布霉素、万古霉素、环丙沙星和庆大霉素敏感;对妥布霉素和环丙沙星耐药性有上升趋势。

Objective To analyze the shifting trends of the results of bacterial culture and antibiotics sensitivity tests in conjunctival sacs of cataract patient before operation in recent yeats. Methods The preoperative conjunctival cultures and antibiotic susceptibility tests of 1964 eyes were studied retrospectively. Results Results The number of positive specimens of bacterial culture in non - infections cataract patients before operation is 894 （45.5%） from 1964 specimens. Gram- positive coocci （G ＋ C） （98.32%）was the most common bacteria isolate ,mainly Staphylococcous epidermidis （64.7） and Staphylococcous aureus （20.2%） ,92.2% of the bacterial isolates were resist- ant to Erythromycinand Penicillin, and most of them were susceptible to Ciprofloxacin, Tobramycin, Vancocin and Gentamycin. The resistant rate of these bacteria to Tobramycin and Ciprofloxacin increased. Conclusion Staphylococcousepidermidis was the mos cataract t frequent bacteria isolate in the conjunctival sac of eyes before cataract surgery. Most of them were resistant to Erythromycin and Penicillin and sensitive to Ciprofloxacin, Tobramycin, Vancocin and Gentamycin. The resistant rate of these bacteria to Tobramycin and Ciprofloxacin increased.