峰峰集团五矿职工及常驻人口掌腱膜挛缩症发病率调查

Investigation of the incidence rate of Dupuytren＇s contracture in Feng Feng Group Co. Wukuang

目的调查掌腱膜挛缩症在我国北方局部地区的发病率。方法调查峰峰集团五矿职工及附近常驻人口掌腱膜挛缩症发病情况，共调查10332人（20662手），约占被调查范围内18周岁以上成年人总数的7．95％。将调查结果填写统一的表格，根据最终的数据计算出掌腱膜挛缩症的发病率并对所得数据进行分析。结果共调查出掌腱膜挛缩症患者60例（72手），计算出本地区掌腱膜挛缩症的发病率为0．581％。61岁以上男性发病率为1.43％。61岁以上组发病率显著高于60岁以下组（P〈0．01）。掌腱膜挛缩共累计95指，以环指发病率最高共56指，显著高于其他指（P〈0．01）。左手发病率明显低于右手（P〈0．01）。男性患者发病率高于女性患者，约为7．6：1（P〈0．01），但性别只是掌腱膜挛缩症发病的一个因素，随着年龄的增长，其他因素在掌腱膜挛缩症发病中的作用开始增加，男女发病率开始接近。酗酒、糖尿病和肺部疾病和本症有高度相关性（P〈0．01）。但掌腱膜挛缩症在国人中与遗传因素的影响较少，与自种人在家族史上有明显差异。结论掌腱膜挛缩症在我国（特别是61岁以上男性）并不是罕见的疾病，我们必须加强专业手外科的建设并提高基层医院的医生对此病的认识。

Objective To investigate the incidence rate of the dupuytren＇s contracture in northern local area. Methods From January 2004 to Augest 2006, 20 662 hands （10 332 adults, the staff of Fengfeng Group Co. Wukuang and nearby residents） were examined, which was about 7.95% of all the residents who axe over 18 years old in this area. All people were asked to fill in the standard form. The dupuytren＇s contracture was diagnozed according the forms. To analyze the incidence rate according to the final data. Results 60 patients （72 hands） suffered from the Dupuytren＇s Contracture. The incidence rate was about 0.581% in this local area. The incidence rate in male over 61 was 1.43%, the percentage which was significantly higher than the male below 60 （P 〈 0.01）. The contracture involved 95 fingers, including 56 ring fingers, which were the most. The incidence was significant higher than the other fingers （P 〈 0.01）. The incidence rate in left hand was significant lower than that of right hand （P 〈 0.01）. The incidence in males significant higher than that in female（P 〈 0.01 ）, and the ratio was about 7.6：1. But gender was just one factor effecting the incidence rate. Along with the increase of age, other factors would take more effects. The incidence rate of male was close to female. Heavy drinking, smoking, diabetes and lung disease had highly association with this disease（P〈 0.01）. Hereditary factors had less effect in Chinese people. It differred from white. Conclusion The Dupuytren＇s Contracture in our country is not a rare disease （especially among men above 61 years）. We must strengthen the construction of Journal specialized hand surgery and improve the good understanding of the disease.