国产药物洗脱支架治疗冠心病九个月随访结果

Safety and efficacy of native drug-eluting stent in patients with coronary heart disease

目的:观察国产药物洗脱支架择期治疗冠心病的临床近、远期疗效。方法:2004年8月至2006年2月择期接受Firebird支架(雷帕霉素洗脱支架)治疗的265例冠心病患者,368支病变血管的401处相关病变置入421枚Firebird支架,随访9个月以上。结果:支架植入成功率100%,30天、6个月、9个月的严重心脏不良事件(包括死亡、再发心肌梗死、靶血管再成形等)分别为1.13%、1.51%、3.77%,血栓形成发生率为0,造影随访率32.01%,9个月的支架内再狭窄率为3.53%。结论:国产药物洗脱支架有良好的临床近、远期疗效。

Objective： To observe the recent and late clinical effects of native drug-eluting stents for treating coronary heart disease （CHD）. Methods： Between August 2004 and February 2006, 256 CHD patients underwent stents implantation, 421 Firebird stents （rapamycin-eluting stents ） were implanted at 401 culprit lesions in 368vessels, followed-up for 9 months. Results： The rate of successful stent implantation was 100%, The rates of major adverse cardiovascular events （including death, reinfarction, and target-vessel revascularizations） were 1.13% on 30 days, 1.51% on 6 months, and 3.77% on 9 months. The rate of thrombosis was 0 in these patients. The re-angiography of follow-up was 32.01% and restenosis was 3.53% in patients with stent implantation for 9 months. Conclusion： Native drug-eluting stents have favorable clinical recent and late clinical effects.