摘要
目的:考察虎杖浓缩片对小鼠环磷酰胺损伤的保护作用。方法:通过对小鼠灌胃给药虎杖浓缩片,腹腔注射环磷酰胺,检测血液白细胞水平。结果:虎杖浓缩片能够抑制环磷酰胺对血液中白细胞的降低,明显升高模型小鼠的白细胞(P<0.01)。结论:虎杖浓缩片对小鼠环磷酰胺损伤有一定的保护作用。
OBJECTIVE To study the protective effect of concentrated tablets of Polygonum cuspidatum（CTPC） on cyclophosphamide injured mice. METHODS The level of leucocyte were observed. Cyclophosphamide was given by ip into mice pretreated with CTPC. RESULTS CTPC obviously inhibited the decrease of leucocyte（P〈0. 01）. CONCLUSION CTPC protected the mice with cyclophoshamide from the injury.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2008年第2期114-116,共3页
Chinese Journal of Hospital Pharmacy
关键词
虎杖
片剂
白细胞
环磷酰胺
Polygonum cuspidatum
tablet
leucocyte
cyclophosphamide
