摘要
用分光光度法测定了5-氟尿嘧啶卟啉与Cu(Ⅱ)配位反应的表观速率常数和表观活化能,用平衡移动法测定了金属卟啉生成反应的平衡常数及热力学相关参数,并探讨了Cd(Ⅱ)对反应的催化作用以及不同溶剂对反应速率的影响。结果表明,H2P与Cu(Ⅱ)配位反应的活化能Ea=64.13kJ/mol,反应的△rHm=-20.552kJ/mol,△rSm=6.787J/mol;Cd2+对反应有催化作用,当Cd2+浓度不大时,速率常数k与Cd2+的浓度成线性关系;溶剂介电常数愈小,反应速率愈大。
Apparent rate constant and apparent activation energy are determined in the coordinate reaction of 5-fluorouracil porphyrin with Cu(Ⅱ) by spectrometry method. Equilibrium constant and related thermodynamic parameters in the formation of metal porphyrin are determined with a mobile equilibrium method, catalysis of Cd (Ⅱ) on the reaction and effect of different solvents on the reaction ratio are discussed. Results show that activation energy in the coordinate reaction of H2P and Cu(Ⅱ) Ea=64.13 kJ/mol, reactive △rHm= -20.552 kJ/mol, △rSm = 6.787 J/mol; Cd2+ has catalysis on the reaction, when the Cd2+ concentration is not big, rate constant k has the linear relationship with Cd2+ concentration; the smaller the dielectric constant is, the bigger the reaction rate is.
出处
《化工生产与技术》
CAS
2008年第1期29-31,共3页
Chemical Production and Technology
基金
湖北省教育厅重点科研项目(2004D005)
关键词
卟啉-Cu(Ⅱ)
动力学
热力学
平衡常数
活化能
催化
porphyrin-copper (Ⅱ)
kinetics
thermodynamics
equilibrium parameter
activation energy
catalysis
