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Synthesis of urea acetates as potential PPARα/γ dual agonists

Synthesis of urea acetates as potential PPARα/γ dual agonists
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摘要 In the quest for novel PPARα/γ dual agonists as putative drugs for the treatment of type 2 diabetes and dyslipidemia, we designed and synthesized a series of urea acetates as potential PPARα/γ dual agonists. The structure of the target compounds, intermediates were characterized by ^1H N-MR, HRMS. In the quest for novel PPARα/γ dual agonists as putative drugs for the treatment of type 2 diabetes and dyslipidemia, we designed and synthesized a series of urea acetates as potential PPARα/γ dual agonists. The structure of the target compounds, intermediates were characterized by ^1H N-MR, HRMS.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2008年第2期166-168,共3页 中国化学快报(英文版)
关键词 Oxazolc PPAR agonist Type 2 diabetes UREA AMMONOLYSIS Synthesis Oxazolc PPAR agonist Type 2 diabetes Urea Ammonolysis Synthesis
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