子痫前期患者高血黏度原因探讨

The Study of the High Blood Viscosity in Preeclampsia

目的:通过测定子痫前期妇女血清血脂和血浆纤维蛋白原水平,探讨其临床意义。方法:对68例子痫前期及32例正常妊娠妇女,采用生化分析仪定量检测空腹血清血脂和血浆纤维蛋白原水平。结果:重度子痫前期患者血清胆固醇、甘油三酯、极低密度脂蛋白和血浆纤维蛋白原水平均明显增高(P<0.05),但轻度子痫前期患者与正常妊娠妇女间差异无显著性。结论:血清胆固醇、甘油三酯、极低密度脂蛋白和血浆纤维蛋白原水平在妊高征患者中明显升高,并与疾病严重程度相一致,而高脂血症和血液的高凝状态均可致子痫前期患者血黏度升高。

Objective：To explore the clinical value of TCHOL, TG, VLDL, Fbg in women with pre-eclampsia. Methods：The levels of TCHOL,TG,VLDL, LDL-C, HDL-C, Fbg in 68 patients and 32 normal prognant women were determined and compared.Results：The revers of serum TC（P 〈0.05）, TG（P 〈0.05）,VLDL（P 〈0.05）, Fbg（P 〈0.05） in women with severe pre-eclampsia group were significant higher than those in control group.The levels of serumTCHOL,TG, VLDL, Fbg were related with the severity of pre-eclampsia. Conlusions： The serum levels otTCHOL,TG,VLDL,Fbg may predict the severity of pre-eclampsia ,and the high level of the serum lipids and Fbg will increase the blood viscosity.