摘要
目的探讨高血压患者血小板4项参数的变化及降压治疗对高血压患者血小板参数的影响。方法采用全血细胞自动分析仪检测32位正常对照者与37名原发性Ⅰ级高血压患者治疗3周前后血压和血小板4项参数指标:血小板计数(PLT)、平均血小板体积(MPV)、血小板分布宽度(PDW)、血小板压积(PCT),统计分析其数据变化。结果高血压时,血小板4项参数均有不同程度增高,降压治疗后,4项指标都有相应回落。结论降压治疗能降低PLT、PCT、MPV与PDW,改善血压升高所致的前血栓状态。
[Objective] To study changes of 4 platelet parameters in primary hypertension patients and discuss the effect of anti-hypertension therapy on the parameters. [Methods] In this trial, 32 healthy people and 37 patients with primary hypertension grade Ⅰ were recruited. Blood pressure and 4 platelet parameters: platelet count (PLT), mean platelet volume (MPV), platelet distribution width (PDW) and platelet hematocrit (PCT) were compared between healthy people and hypertension patients, and were also compared before and after 3 weeks of anti-hypertension therapy; the 4 platelet parameters were performed by the whole blood automatic analysis apparatus. [Results] The 4 platelet parameters were increased in hypertension patients compared with healthy people and decreased after anti-hypertension therapy. [Conclusion] Anti-hypertension therapy can reduce PLT, PCT ,MPV and PDW of platelets, and ameliorate the pre-thrombus state of hypertension.
出处
《中国医学工程》
2007年第10期831-833,共3页
China Medical Engineering
关键词
高血压
血小板
参数
降压治疗
primary hypertension
platelet
parameters
anti-hypertension therapy