新生儿轮状病毒感染的探讨(附89例分析)

Studies on the Rotavirus Infection in Newborns

目的：探讨新生儿时期轮状病毒感染的情况。方法：用酶联免疫吸附试验（ＥＬＩＳＡ）对８９例新生儿的粪便、唾液分别进行Ａ组轮状病毒（ＲＶ）检测，其中同时检测２０例母亲粪便、乳汁ＲＶ。结果：粪便轮状病毒检出率６８．５％，唾液ＲＶ检出率５３．９％。粪阳性者中无症状者达８３．６％，粪便、唾液检出率与日龄间无明显关系（Ｐ＞０．０５）；母乳喂养者粪便、唾液检出率明显低于人工喂养者（Ｐ＜０．０１或＜０．０５）。结论：新生儿时期轮状病毒感染率高，大多为无症状者，少数有腹泻者症状亦较轻。

Objective:To investigate the rotavirus infection in newborns. Methods: We detected Group A rotavirus by ELISA in the stool and saliva of 89 cases,simultaneously detected that rotavirus in the mother's stool and milk of 20 cases.Results:The data revealed that the positive rate in stool was 68.5%,in saliva was 53.9%.Asymptomatic rate of stool positive patients was 83.6%.The detection rate in stool or saliva has no apparent relationship to the day-old(P>0.05),The stool or saliva detection positive of mother feeding patients was evidently than that of artificially feeding patients (P<0.01,P<0.05).Conclusion:Rate of rate of rotavirus infection in newborns was higher,but most of them was asymptomatic,a small number of diarrhoea patients wae not at all serious.