多沙唑嗪治疗原发性高血压38例疗效观察

The effect of doxazosin mesylate therapy on 38 patients with essential hypertension

目的观察多沙唑嗪治疗原发性高血压的临床疗效。方法38例Ⅰ或Ⅱ期原发性高血压患者服用多沙唑嗪控释片4～8mg／d，4周，观察治疗前后诊所血压（CBP）、超声心动图及生化指标的变化。结果多沙唑嗪治疗后血压下降明显，总有效率87％，对血糖、血脂和心功能无不良影响。结论多沙唑嗪是治疗高血压的有效药物，安全、耐受性好。

Objective To observe the effect of doxazosin mesylate（cardur） on essential hypertension. Methods The experiment was carried out by choosing 38 patients with essential hypertensive phase Ⅰ or Ⅱ to receive doxazosin（cardura） therapy. Clinic blood pressure （CBP）, ultrasonic cardiogram （UCG） and biochemic exams were investigated. Results The total effective rate was 87 % . No harmful reaction of blood glucose, blood lipid and cardiac function were found. Conclusion It was effective and safe that doxazosin was treated on essential hypertension patients with mild-moderate essential hypertension.