期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

抗心肌缺血／再灌注损伤新方案--缺血后处理 被引量：1

New plan against myocardial ischemia reperfusion——ischemic post-conditioning
下载PDF
导出
摘要 缺血后处理是最近提出的一种具有心肌保护作用的治疗措施,由于可在心肌缺血发生后实施,临床可控性强,因而比缺血预处理具有更直接、广泛的临床应用价值,现就其在心肌保护机制的探讨做一综述。 Ischemic post- conditioning is a novel therapeutic method. Because it can be applied after myocardial ischemia with highly clinical controllability, ischemic post -conditioning has more direct and wide clinical application value than ischemic pre - conditioning. This review discusses the mechanisms of post - conditioning.
作者 杨美婷 高航
机构地区 辽宁医学院心血管内科 辽宁医学院附属第一医院心血管内科
出处 《中国急救医学》 CAS CSCD 北大核心 2008年第2期167-169,共3页 Chinese Journal of Critical Care Medicine
关键词 心肌缺血 缺血后处理 再灌注损伤 心肌保护 Myocardial ischemia Ischemie post - conditioning Reperfusion injury Myo -cardial protection
分类号 R541 [医药卫生—心血管疾病]
  • 相关文献

参考文献17

  • 1Zhao ZQ,Corvera JS,Halkos ME,et al. Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning[ J ]. Am J Physiol Heart Circ Physiol, 2003, 285(2) :H579 -588.
  • 2Galagudza M, kurapeev D, Minasian S, et al. lschemic postconditioning:brief ischemia during reperfusion converts persistent ventricular fibrillation into reglar rhythm [ J ] Eur Cardiothoracsurg, 2004,25 : 1006 - 1010.
  • 3Kin H, Zatta AJ ,LofyeMT, et al. Postconditioning reduces infarct size via adenosine receptor activation by endogenous adenosine [ J ]. Cardiovasc Res ,2005,67 ( 1 ) : 124 - 133.
  • 4Yang XM, Proctor JB, CuiL, et al. Multip le, brief coronary occlusions during early rcpcrfusion protect rabbit hearts by targeting cell signaling pathways [ J ] . J Am Coll Cardiol, 2004,44 ( 5 ) : 1103 - 1110.
  • 5Krolikowski JG, Weihrauch D, Bienengraeber M,et al. Role of Erk1P2, p70s6K,and eNOS in isoflurane- induced cardioprotection during early reperfusion in vivo [ J ]. Can J Anaesth ,2006,53 (2) : 174 - 282.
  • 6Zhao ZQ, Vinten, Johansen J. Postconditioning: Reduction of reperfusion induced injury[J]. Cardiovasc Res,2006,70(2) :200-211.
  • 7Hausenloy D J, TsangA, Yellon DM, et al. The reperfusion injury salvage kinase pathway:A common target for both ischemic preconditioning and postconditioning[ J ]. Trends Cardiovasc Med, 2005,15 : 69 - 75.
  • 8Tsang A, Hausenloy DJ, MocanuMM, et al. Postconditioning: A form of "modified reperfusion" protects the myocardium by activating the phosphatidy linositol -3 -kinase- Akt pathway [ J ]. Circ Res ,2004, 95(3) :230 -232.
  • 9Darling CE ,J iang R, MaynardM, et al. Postconditioning via stuttering reperfusion limits myocardial infarct size in rabbit hearts: role of ERK1/2 [J] . Am J Physiol Heart Circ Physiol, 2005,289 ( 4 ) : H1618 - 1626.
  • 10Philipp SD, Yang XM, Cui L, et al. Postconditioning protects rabbit hearts through a protein kinase C adenosine A(2b) receptor cascade [J]. Cardiovasc Res,2006,70 (2) :308 - 314.

同被引文献5

引证文献1

二级引证文献2

中国急救医学
2008年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部