普卢利沙星片溶出度测定方法研究

Study on dissolution test of prulifloxacin tablets

目的:建立紫外分光光度法测定普卢利沙星片溶出度。方法:以0.1 mol·L^(-1)盐酸作为溶剂,测定波长274 nm。结果:线性范围为1～10μg·mL^(-1),r=0.9999,平均回收率为100.0%(n=9)。结论:本方法简便,结果准确。

Objective：To establish a ultraviolet spectrophotometry Prulifloxacin Tablets. Methods：0. 1 mol · L^-1 HCl as dissolution The linearity of calibration curve was in the range of 1 - 10 p.g method for the determination of dissolution test of medium, and the detection at 274 nm. Results： The linearity of calibration curve was in the range of 1 - 10 μg · mL^-1 , and the correlation coefficient was r = 0. 9999. The average recovery was 100. 0% （ n = 9）. Conclusion： The method is easy to operate and the results of the determination is accurate.