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幽门螺杆菌与特发性血小板减少性紫癜发病关系的研究进展 被引量：11

Progress in the pathogenesis of helicobacter pylori associated idiopathic thrombocytopenic purpura
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摘要 幽门螺杆菌(Hp)感染与特发性血小板减少性紫癜(ITP)的发病有关。约50%Hp阳性ITP患者根除Hp后血小板减少症得以完全或部分缓解。目前Hp相关ITP的发病机制尚不完全清楚,此文就其发病机制研究进展作一综述。 Several recent studies have documented that Hp is involved in the causes of idiopathic thrombocytopenic purpura. Approximately 50% idiopathic thrombocytopenic purpura patients with Hp infection achieved complete or partial platelet recovery after Hp eradication. This article reviews progress in the pathogenesis of Hp associated idiopathic thrombocytopenic purpura.
作者 赵瑾 季峰
机构地区 浙江大学医学院附属第一医院消化科
出处 《国际消化病杂志》 CAS 2008年第1期20-22,31,共4页 International Journal of Digestive Diseases
关键词 特发性血小板减少性紫癜 幽门螺杆菌 发病机制 Idiopathic thrombocytopenic purpura Helicobacter pylori Pathogenesis
分类号 R554.6 [医药卫生—血液循环系统疾病] R573.1 [医药卫生—消化系统]
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参考文献20

  • 1Gasbarrini A, Franceschi F, Tartaglione R, et al. Regression of autoimmune thrombocytopenia after eradication of H. pylori. Lancet, 1998,352:878.
  • 2Takahashi T, Yujiri T, Shinohara K, et al. Molecular mimicry by H. pylori CagA protein may be involved in the pathogenesis of H. pylori-associated chronic idiopathic thrombocytopenic purpura. Br J Haematol, 2004,124: 91-96.
  • 3Kohda k, Kuga T, Kogawa K, et al. Effect of H. pylori eradication on platelet recovery in Japanese patients with chronic idiopathic thrombocytopenic purpura and secondary autoimmune thrombocytopenic purpura. Br J Haematol, 2002, 118: 584-588.
  • 4Inaba T, Mizuno M, Take S, et al. Eradication of Helicobacter pylori increases platelet count in patients with idiopathic thrombocytopenic purpura in Japan. Eur J Clin Invest, 2005, 35:214- 219.
  • 5Nomura S, Inami N, Kanazawa S. The effects of Helicobacter pylori eradication on chemokine production in patients with immune thrombocytopenic purpura. Eur J Haematol, 2004, 72: 304 -305.
  • 6Franceschi F,Christodoulides N,Kroll M H, et al. Helicobacter pylori and idiopathic thrombocytopenic purpura. Ann Intern Med, 2004, 140:766-767.
  • 7Suzuki T, Matsushima M, Masui A, et al. Effect of Helicobacter pylori eradication in patients with chronic idiopathic thrombocytopenic purpura-A randomized controlled trial. Am J Gastroenterol, 2005, 100 : 1265-1270.
  • 8Asahi A, Kuwana M, Suzuki H, et al. Therapeutic action of Helicobacter pylori eradication patients with chronic ITP - Lessons from eradication therapy on H-pylori negative patients. Blood, 2004, 104: 2070.
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二级参考文献10

  • 1Emilia G,Longo G,Luppi M,et al.Helicobacter pylori eradication can induce platelet recovery in idiopathic thrombocytopenic purpura.Blood,2001,97:812-814.
  • 2Veneri D,Krampera M,Franchini M.High prevalence of sustained remission of idiopathic thrombocytopenic purpura after Helicobacter pylori eradication:a long-term follow-up study.Platelets,2005,16:117-119.
  • 3Takahashi T,Yujiri T,Shinohara K,et al.Molecular mimicry by Helicobacter pylori CagA protein may be involved in the pathogenesis of H.pylori-associated chronic idiopathic thrombocytopenic purpura.Br J Haematol,2004 ,124:91-96.
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  • 5Ando T,Tsuzuki T,Mizuno T,et al.Characteristics of Helicobacter pylori-induced gastritis and the effect of H.pylori eradication in patients with chronic idiopathic thrombocytopenic purpura.Helicobacter,2004,9:443-452.
  • 6Suzuki T,Matsushima M,Masui A,et al.Effect of Helicobacter pylori eradication in patients with chronic idiopathic thrombocytopenic purpura-a randomized controlled trial.Am J Gastroenterol,2005,100:1265-1270.
  • 7Jarque I,Andreu R,Llopis I,et al.Absence of platelet response after eradication of Helicobactcr pylori infection in patients with chronic idiopathic thrombocytopenic purpura.Br J Haematol,2001,115:1002-1003.
  • 8Michel M,Cooper N,Jean C,et al.Does Helicobacter pylori initiate or perpetuate immune thrombocytopenic purpura? Inside Blood,2004,103:890-896.
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  • 10王兆钺 陈德春 徐潇.抗人血小板单克隆抗体对花生四烯酸代谢的影响[J].中华血液学杂志,1987,8:385-387.

共引文献11

同被引文献92

引证文献11

二级引证文献39

国际消化病杂志
2008年 第1期

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