口服乳果糖溶液对蛛网膜下腔出血后便秘的预防

Prevention effect of lactulose oral solution on constipation after subarachnoid hemorrhage

目的探讨口服乳果糖口服溶液对蛛网膜下腔出血后便秘的预防。方法将200例首发蛛网膜下腔出血患者随机分为实验组和对照组,实验组口服乳果糖口服液患者75例。对照组未服乳果糖口服液患者125例,给予常规护理。实验组在常规护理的基础上,于入院后即口服乳果糖口服液10ml,2次/d,连续口服10d。记录患者每天的排便情况。结果对照组蛛网膜下腔出血后便秘的发生率为40.8%,实验组蛛网膜下腔出血后便秘的发生率为25.3%,2组有显著性差异（P〈0.05）。结论口服乳果糖口服液对蛛网膜下腔出血后便秘有较好的预防作用,且口服方便,易于被患者和家属接受。

Objective To investigate the prevention effect of lactulose oral solution on constipation after subarachnoid hemorrhage. Methods 200 patients who firstly suffered from subarachnoid hemorrhage were randomly divided into the experiment group （n = 75） who received the usual care and the oral administration of lactulose oral solution, and the control group （n = 125） who received the usual care Only. The experiment group received 10ml of lactulose oral solution immediately after hospitalization on the basis of the usual care （administrating twice a day and lasting ten days）. We used Rome Ⅱ as the diagnostic criteria to assess the constipation after subarachnoid hemorrhage. Results The incidence rate of constipation after subarachnoid hemorrhage in the control group was 40.8% （51/125）, whereas it was 25.3% in the experimental group （51/125）. There was a significant difference between the two groups （P 〈 0.05）. Conclusions Oral administration of lactulose oral solution has good prevention effect on constipation after subarachnoid hemorrhage, and is of convenience and easy to be accepted by the patients and their families.