期刊文献+

运动神经元病的临床观察与护理 被引量:4

下载PDF
导出
摘要 运动神经元病是一组选择性侵犯脊髓前角细胞、脑干后组运动神经元、皮质锥体细胞及锥体束的慢性进行性变性疾病。临床上兼有上和/或下运动神经元受损的体征,表现为肌无力、肌萎缩和锥体束征的不同组合,感觉和括约肌功能一般不受影响。目前病因未明,可能与遗传、中毒、免疫、病毒感染等因素有关。肌萎缩性侧索硬化是运动神经元病最常见的类型。多在40岁以后发病,
出处 《现代护理》 2008年第4期527-528,共2页 Modern Nursing
  • 相关文献

参考文献3

  • 1王维志.神经病学[M].5版.北京:人民卫生出版社,2005:221-224.
  • 2王耀辉,徐德保,丁玉兰.实用专科护士丛书一神经内科、外科分册[M].长沙:湖南科学技术出版社,2004:221-223.
  • 3王运良,曹芳,耿爽.肌萎缩性侧索硬化的研究进展[J].实用医药杂志,2004,21(2):165-167. 被引量:12

二级参考文献15

  • 1Traynor BJ,Codd MB,Corr B,et al.Clinical features of amyotrophic lateral sclerosis according to the E1 Escorial and Airlie House diagnostic critefia:a population-based study. Arch Neurol, 2000,57:1171.
  • 2Rowland LP. Diagnosis of amyotrophic lateral sclerosis, J Neurol Sci, 1998,160:suppl 1:s6.
  • 3Chalabi A,Anderson PM, Chioza B, et al, Recessive amyotrophic lateral sclerosis families with the D90A SOD1 mutation share a common founder, evidence for a linked protective factor.Hun Mol Genet,1998,7:2045.
  • 4Rowland LP. Molecular basis of genetic heterogeneity:role of the clinical neurologist. J Child Neurol, 1998,13:122.
  • 5Anderson PM,Nilsson P,Keranen ML,et al.Phenotypic heterogeneity in motor neuron disease patients with Cu Zn-superoxide dismutase mutations in Scandinavia. Brain,1997,120:1723.
  • 6Berger MM,Kopp N,Vital C,et al.Detection and cellular localization of enterovirus RNA sequences in spinal cord of patients with ALS, Neurology,2000,54:20.
  • 7Apple S. ALS: immune factors in motor neuron cell injury. In:Neurobiology of ALS:education program syllabus.Amerlcan Academy of Neurology, 1999,1:101.
  • 8Estevez AG,Crow JP, Sampson JB, et al. Induction of nitric oxide-dependent apoptosls in motor neurons by zine-deficient superoxide dismutase. Science, 1999,286:2498.
  • 9Cleveland DW,Liu J. Oxidation versus aggregation-how do SOD1 mutants cause ALS? Nat Med,2000,6:1320.
  • 10Julien JP,Beaulieu JM.Cytoskeletal abnormalities in amyotrophic lateral sclerosis:beneficial or detrimental effects? J Neurol Sci,2000,180:7.

共引文献13

同被引文献12

引证文献4

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部