摘要
骨肉瘤是一种起源于间叶组织的恶性肿瘤,是骨骼系统最常见的恶性肿瘤,多发于青少年。手术、放化疗对骨肉瘤的疗效仍然有限,新辅助化疗、生物靶向治疗、免疫疗法及中医中药已成为骨肉瘤治疗新的发展方向,但骨肉瘤治疗研究仍有待新的突破。2007年ASCO会议报告了有关骨肉瘤治疗最新研究进展,本文结合目前国内外研究对骨肉瘤的内科治疗现状作一浅要综述。
Osteosarcoma, derived from mesenchymal tissue, is the most frequent malignant tumor in skeletal system. It is the third most common malignancy in children and adolescents. Up to now, limited curative effects are achieved in operation, chemotherapy and radiotherapy in the treat- ment of osteosarcoma. Prospective therapeutic effects have been confirmed in new therapies including neoadjuvant chemotherapy, bio-targeted therapy, immunotherapy, and traditional Chinese medicine, although further breakthrough is still on the way. We summarize the recent advances in osteosarcoma treatment along with highlights reported in ASCO 2007.
出处
《癌症进展》
2008年第1期47-52,共6页
Oncology Progress
关键词
骨肉瘤
化疗
靶向治疗
osteosarcoma chemotherapy targeted therapy
