大承气汤对急性胰腺炎患者腹腔内压的影响

Effect of Dachengqi(大承气) Decoction on Intra-abdominal Pressure in Patients with Acute Pancreatitis

目的:探讨大承气汤对急性胰腺炎患者腹腔内压的影响。方法:60例患者随机分为两组,观察组给予常规治疗外加用大承气汤保留灌肠7d,对照组只给予常规治疗加生理盐水灌肠。检测两组患者膀胱内压(ICP)值以评价腹腔内压变化。结果:观察组ICP值于治疗期第4、5d时较对照组低,治疗第3dICP值开始下降,对照组第5d开始出现ICP值下降。结论:大承气汤有降低急性胰腺炎患者腹腔内压的作用,对防治腹腔室间隔综合征(ACS)有一定意义。

Abstract：Objective To investigate the effect of Daehengqi（大承气）decoction on intra-abdominal pressure （IAP） in patients with acute panereatitis （AP）.Methods Sixty patients with AP were randomly divided into two groups,30 patients were administered Daehengqi decoction clysis for 2 hours everyday for 7 days;the other 30 were treated with NS clysis and conventional treatment.The intraeystic pressure （ICP） of the two groups patients was tested during treatment period.Results The levels of ICP in the experimental group decreased the third day and were lower than those in control group on the forth and fifth treatment days;while in control group those decreased from the fifth day.Conclusion Daehengqi decoction can lower the level of ICP and thus IAP in patients with AP,which is significant in prevention and treatment of abdominal compartment syndrome.