1Billy E,Brondani V,Zhang H,Muller U,Filipowicz W.Specific interference with gene expression induced by long,doublestranded RNA in mouse embryonal teratocarcinoma cell lines.Proc Natl Acad Sci U S A 2001:98:14428—14433.
2Krichevsky AM,Kosik KS.RNAi functions in cultured mammalian neurons.Proc Natl Acad Sci U S A 2002；99:11926—11929.
3Sui Gf Soohoo C,Affar elB?Gay F,Shi Y?Forrester WC? Shi Y.A DNA vector··based RNAi technology to suppress gene expression in mammalian cells.Proc Natl Acad Sci U S A 2002；99:5515—5520.
4McCaffrey APf Meuse L?Pham TT,Conklin DS?Hannon GJ? Kay MA.RNA interference in adult mice.Nature 2002；418:38—39.
5Stewart SAf Dykxhoorn DM,Palliser D,Mizuno H?Yu EY?An DS,Sabatini DM,Chen IS,Hahn WC,Sharp PA?Weinberg RA? Novina CD.Lentivirus—delivered stable gene silencing by RNAi in primary cells.RNA 2003；9:493—501.
6Paddison PJ,Caudy AA,Bernstein E,Harmon GJ,Conklin DS.Short hairpin RNAs(shRNAs)induce sequence—specific silencing in mammalian cells.Genes Dev 2002；16:948—958.
7Hemann MT,Fridman js,Zilfou JT,Hernando E,Paddison PJ,Cordon—Cardo C,Hannon GJ,Lowe SW.An epi—allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo.Nat Genet 2003；33:396—400.
8Paul CP|Good PD,Winer I,Engelke DR.Effective expression of small interfering RNA in human cells.Nat Biotechnol 2002；20:505-508.
9Kennerdell JR,Carthew RW.Heritable gene silencing in Drosophila using double-stranded RNA.Nat Biotechnol 2000；18:896—898.
10Kasschau KD。Xie Z,Allen E,Llave C,Chapman EJ,Krizan KA,Carrington jc.P1／HC—Pro,a viral suppressor of RNA silencing,interferes with Arabidopsis development and miRNA unction.Dev Cell 2003；4:205—217.
