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黄芪对寻常型银屑病患者IL-6、IL-8及IL-10血浆水平的影响 被引量:3

The effects of astragalus membranaceus on plasma interleukin-6、interleukin-8 and interleukin-10 of Psoriasis Vulgaris at progressive stage
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摘要 目的研究黄芪对进展期寻常型银屑病患者血浆IL-6、IL-8与IL-10水平的影响。方法采用放射免疫法检测57例进展期寻常型银屑病患者用黄芪治疗前后血浆IL-6、IL-8与IL-10水平的变化。结果黄芪能降低血浆中过高的IL-6、IL-8水平(P<0.01),升高IL-10水平(P<0.05)。结论黄芪能通过调节细胞因子与淋巴细胞功能而治疗银屑病。 Objective To investigate the effect of astragalus membranaceus on plasma levels of inter- leukin-6,interleukin-8 and interleukin-10 in patients with Psoriasis Vulgaris at progressive stage. Methods Blood samples were taken before and after treatment with astragalus membranaceus, and the plasma levels of IL- 6,IL-8 and IL-10 in 57 psoriatic patients were measured by ELISA. Results Astragalus membranaceus has the actions of reducing plasma levels of IL-6 ,IL-8 and elevating the level of IL-10 in progressiving Psoriasis Vulgaris. Conclusion Astragalus membranaceus can treat Psoriasis Vulgaris by targeting at the cytokines and modulating lymphocytic function.
出处 《中国实用医药》 2008年第7期31-32,共2页 China Practical Medicine
关键词 银屑病 黄芪 白细胞介素(IL) Psoriasis Astragalus membranaceus Interleukin
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  • 1[3]Arican O,Aral M.sesmas S,et al.Serum levels of TNF-alpha,IFNgamma,IL-6,IL-8,IL-12,IL-17,and IL-18 in patients with active psoriasis and correlation with disease serity.Mediators Inflamm,2005,5:273-279.
  • 2[4]Abanmi A,AI Harthi F,Al Agla R,et al.Serum levels of proinflammatory eytokines in psoriasis patients from Saudi Arabia.Int J Dermatol,2005,44(1):82-83.
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  • 4李晓民,史立宏,李敏,孙文起.黄芪颗粒治疗寻常型银屑病疗效观察[J].中国麻风皮肤病杂志,2007,23(1):90-91. 被引量:6

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