摘要
乙型肝炎病毒(HBV)感染可引起急性和慢性乙型肝炎,最终可能导致肝硬化、肝癌等严重后果。作为一种可以帮助生物抵抗外在感染的体内防御机制,近年来RNA干扰已成为人们进行抗感染和基因治疗研究的有力工具。本文对RNA干扰技术在抗HBV感染方面的研究进展进行综述。
The infection of HBV may cause acute and chronic hepatitis B, and potentially lead to hepatocirrhosis and liver cancer. As a defense mechanism of organism to resist external infection, RNA interference （RNAi） has become a powerful tool for us to study its effects on antiviral infection and gene therapy in recent years. In this article we summarize the mechanisms of RNA interference and the progress on anti-HBV infection studies by RNAi.
出处
《基础医学与临床》
CSCD
北大核心
2008年第2期198-200,共3页
Basic and Clinical Medicine
基金
广东省科技攻关计划项目(2005B10401034)
