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急诊经皮穿刺置入支架治疗无保护左主干为主的病变28例 被引量:1

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摘要 目的:探讨急诊经皮冠状动脉介入(percutaneous coronary intervention,PCI)治疗无保护冠状动脉左主干(unprotected left main coronary artery,UPLMCA)为主的冠状动脉粥样硬化性病变的疗效。方法:于发病8 h内采用PCI治疗UPLMCA病变患者28例(LVEF均等于或大于0.45)。术前30 min口服阿司匹林300 mg、氯吡格雷300 mg或噻氯匹定500 mg,并予低分子量肝素5 000 U皮下注射。根据冠状动脉造影结果按常规方法于左主干置入支架,对合并左前降支、左回旋支或右冠状动脉病变者先予以常规的经皮腔内冠状动脉成形术处理,再行左主干的支架置入。左主干的支架置入均为直接置入,支架球囊释放压力14~18 atm,扩张时间2~3 min,重复造影,如效果不满意者,予支架球囊原位增加2~4 atm压力再扩张。结果:手术即刻成功率100%。所有患者置架处血流均达TIMIⅢ级。所有患者术后心绞痛症状消失。随访5~11个月,仅1例术后2个月出现梗死后综合征(经处理后好转),其余患者情况稳定。结论:对于LVEF等于或大于0.45的UPLMCA病变患者,及早行PCI的疗效较好。
出处 《新医学》 北大核心 2008年第2期90-92,共3页 Journal of New Medicine
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