河北省某市艾滋病流行特征分析

Analysis on Characteristics of HIV/AIDS Epidemic in a Certain City of Hebei Province

目的分析某市艾滋病病毒/艾滋病(HIV/AIDS)流行现状、特征及趋势。方法依据该市1989-2006年AIDS常规监测、高危人群哨点监测,流行病学调查及实验室资料,建立数据库并进行综合分析。结果自1989年发现首例HIV感染者至2006年底,累计发现HIV抗体阳性者240例,其中AIDS病人60例,死亡82例。HIV感染者/AIDS病例主要分布在沙河市。从市外既往有偿供血者传入为主转向境内蔓延扩散,经可疑受血感染是该市HIV传播的主要途径,青壮年女性感染率较高。HIV-1型B’亚型、CRF-BC重组株是该市主要流行株。结论该市艾滋病呈低流行状态,局部地区呈聚集性升高,经可疑受血传播HIV已被阻断。

Objective To analyze the prevalence, features, and trend of HIV/AIDS in a certain city of Heibei Province. Methods The database was established according to the data of routine surveillance, sentinel surveillance for high risk population, epidemiology surveys, as well as laboratory testing records from 1989 to 2006, and then the data were conducted comprehensive analysis. Results Since the first HIV infected case was found in 1989, the total HIV antibody positive patients reached 240 by the end of 2006, 60 cases were AIDS patients and 82 patients died. The HIV/AIDS cases were mainly distributed in Shahe. The HIV/AIDS cases were fetched abroad by former paid blood donors and the HIV carrier cases spread locally from abroad were increasing. The major route of transmission was through blood transfusion, and the positive rate of HIV was high among young- adult women in Shahe. The dominant strains of HIV - 1 were subtype B＇ and CRF - BC recombi- nant strain. Conclusion The current prevalence of HIV/AIDS is low in this city, however, the prevalence of HIV is concentratedly increased in some areas. The results suggest that HIV transmission through blood transfusion is controlled in this city.