颈动脉粥样硬化与脑梗死复发的关系

The relationship between carotid atherosclerosis and recurrence of cerebral infarction

目的探讨颈动脉粥样硬化与脑梗死复发的关系。方法连续收集急性脑梗死住院患者268例,通过颈动脉彩超检查颈动脉粥样硬化情况,随访观察有无脑梗死复发。结果随访12个月内,268例脑梗死患者有25例(9.33%)复发脑梗死,复发和未复发脑梗死患者颈动脉斑块检出率差异无统计学意义(P>0.05);复发脑梗死患者低回声、混合性回声斑块的出现率及颈总动脉、颈动脉分叉处血管内中膜厚度值明显高于未复发患者(P<0.05)。结论颈动脉内中膜厚度增厚及伴有低回声和混合密度回声斑块患者脑梗死复发率增高。

Objective To investigate the relationship between carotid atherosclerosis（CAS）and recurrence of acute cerebral infarction（ACI）with ultrasonography.Methods We consecutively recruited 268 patients with acute cerebral infarction,and ultrasonography was performed to evaluate the situation of CAS.All patients were followed-up prospectively and the outcome of recurrence of cerebral infarction was observed.Results Among 268 patients with ACI,recurrence was seen in 25 of them（9.33%）in 12 months follow-up period.The frequency of plaque occurred in carotid artery among patients with recurrence of CI or free of recurrence of CI had no significant difference（P〉0.05）.Frequency of occurrence of soft plaque,complex plaque and values of intima-media thickness（IMT）at common carotid artery（CCA）and bifurcation（BIF）are higher in patients with recurrence of ACI than those with free of CI recurrence（P〈0.05）.Conclusion Increased CCA-IMT values,soft plaque and complex plaque are associated with a higher risk of long-term stroke recurrence.