急诊介入治疗高危不稳定性心绞痛的临床研究

Clinical study of emergent intervention for high risk unstable angina pectoris

目的研究急诊介入治疗高危不稳定性心绞痛(UAP)的效果及安全性。方法71例UAP患者入院后随机分为两组:急诊介入治疗组43例,非急诊介入治疗组28例。均行冠脉造影和介入治疗。观察30d内心脏事件(包括心绞痛、急性心肌梗死、猝死、再次介入治疗及冠脉搭桥手术)的发生率,症状缓解率,症状缓解时间,住院时间及住院费用。结果急诊介入治疗与非急诊介入治疗组比较,急诊介入治疗UAP降低了30d内心脏事件(心绞痛、急性心肌梗死、猝死)的发生,差异具有显著性(P<0.05);缩短了症状缓解及住院时间,差异具有显著性(P<0.05);降低住院费用,具有显著性差异(P<0.05);而手术的成功率及疗效相似,差异无显著性(P>0.05)。结论急诊介入治疗高危的UAP患者效果好,安全,并可缩短住院时间,降低住院费用。

Objective To investigate the efficacy and safety of intervention for high risk unstable angina pectoris（UAP）.Methods Seventy one patients with high risk UAP were randomly divided into emergent intervention group（43 patients）and non-emergent intervention group（28 patients）.All the patients were performed coronary angiography and intervention.The cardiac events（including angina pectoris,acute myocardial infarction,sudden death,reintervention and coronary artery bypass surgery）within 30 days,symptom relief rate,symptom relief time,duration of hospitalization and hospitalization expenditure were recorded.Results Compared with non-emergent intervention group,emergent intervention decreased cardiac event（angina pectoris,acute myocardial infarction and sudden death）rates within 30 days（P〈0.05）,shortened symptom relief time and hospitalization time（P〈0.05）and decreased hospitalization expenditure（P〈0.05）.However,the success rate of operation and treatment efficacy were identical between two group（P〉0.05）.Conclusion Emergent intervention for high risk unstable angina pectoris is effective,safe,and also can shorten hospitalization time,decrease expenditure.