108株铜绿假单胞菌的临床分布与药敏结果

Clinical distribution and drug sensitivity of 108 strains of Pseudomonas aeruginosa

目的探讨引起医院感染的铜绿假单胞菌的临床分布及其药敏结果分析。方法用常规方法将临床送检的各种标本进行分离培养,用TDR-1002型细菌鉴定及药敏测试仪进行细菌鉴定和观察药敏。结果检出菌株数及标本来源所占比例依次为:痰48株(44.5%),分泌物29株(26.8%),尿液19株(17.6%),脓液7株(6.5%),导管3株(2.7%),血液2株(1.9%),共计108株。临床上对该菌比较敏感的抗生素分别为阿米卡星、美洛培南、头胞吡肟、妥布霉素,而对青霉素类及头胞类抗生素的耐药率普遍偏高。结论通过药敏试验提示临床医生应合理选用抗生素,减少耐药菌株的产生。

Objective To investigate the clinical distribution and drug sensitivity of Pseudomonas aeruginosa which leads to hospital infection. Methods Various kinds of clinical species were isolated and cultured with conventional method. TDR-1002 bacteria identification and drug sensitivity analyzer was applied. Results A total of 108 strains were detected. The distribution of the detected strains were as follows：phlegrn 48 strains （44.5%）, secretion 29 strains （26.8%）, urine 19 strains （17. 6%）, liquor puris 7 strains （6.5%）, catheter 3 strains （2. 7%）, and blood 2 strains （1.9 %）. The more sensitive antibiotics were arnikacin, rneropenern, cefepirne and tobrarnycin, and while it was high resistant to penicillins and cephalosporins. Conclusion Drug sensitivity test shows antibiotics should be chosen rationally to reduce the occurence of drug resistant strains.