摘要
用不同脉冲电场和磁场上升沿的平均变化率,分别作用于小鼠,每天平均4 h,15 d后检测小鼠肝脏组织中的丙二醛(MDA)含量及谷胱甘肽过氧化酶(GSH2px)活性.脉冲电场和磁场暴露的小鼠,肝组织中MDA含量较对照组明显减少(P<0.01),GSH2px活性明显增加(P<0.01).随着脉冲电场和磁场平均变化率的增大,实验组小鼠肝组织中MDA含量及GSH2px活性变化更加明显,提示一定强度的脉冲电场和磁场可以影响小鼠肝组织的脂质过氧化代谢,提高抗氧化酶的活力,降低氧化物的生成,对延缓衰老有积极作用.
The effects of pulse electric and magnetic field on the malonaldehyde （MDA） and glutathione peroxidase of hepatic tissue were studied. The magnetic induction intensity inside the coils and its rising time from zero Tesla to the maximum were calculated. Different pulse electric and magnetic field with averaged change rates of rising edge were applied to mice for 4 hours per day. After 15 days,the MDA and glutathione peroxidase of hepatic tissue were detected. Compared with control group,MDA content decreased and GSH2px activity increased obviously, when mice exposed in pulse electric and magnetic field （P〈0.01）. Pulse electric and magnetic field can affect the lipid peroxidation of mouse hepatic tissue, improve the activity of antioxidase and decrease production of oxide.
出处
《内蒙古师范大学学报（自然科学汉文版）》
CAS
2008年第1期61-62,66,共3页
Journal of Inner Mongolia Normal University(Natural Science Edition)
关键词
谷胱甘肽过氧化酶
丙二醛
脉冲电场和磁场
Glutathione Peroxidase
Malonaldehyde（MDA）
pulse electric and magnetic field
