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携带前强啡肽基因重组质粒的构建及鉴定 被引量:7

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摘要 强啡肽(dynorphin)是作用于κ-阿片受体的神经肽,广泛分布于外周和中枢神经系统,涉及到许多生理和病理变化如吗啡耐受和依赖等。我们利用前强啡肽基因(prodynorphin gene)构建pUC57-prodynorphin重组质粒为下一步探讨其在吗啡耐受和依赖中的作用奠定了基础。
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2008年第2期142-142,共1页 Chinese Journal of Experimental Surgery
基金 国家自然科学基金资助(30770702) 广东省自然科学基金资助(06024112)
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  • 1McClung CA, Nestler EJ, Zachariou V. Regulation of gene expression by chronic morphine and morphine withdrawal in the locus ceruleus and ventral tegmental area. J Neurosci, 2005,25:6005-6015.

同被引文献29

  • 1曲敏,罗俊生.骨髓基质细胞诱导分化为神经细胞的研究进展[J].解剖科学进展,2006,12(2):175-178. 被引量:4
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