期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

跨膜丝氨酸蛋白酶4和癌胚纤维连接蛋白在甲状腺癌中的表达 被引量：3

原文传递
导出
摘要 甲状腺癌是头颈部最常见的恶性肿瘤，约占全身恶性肿瘤的1％左右。本实验探讨了甲状腺癌、良性病变和癌旁组织中跨膜丝氨酸蛋白酶4（TMPRSS4）和癌胚纤维连接蛋白（onfFN）mRNA的表达与甲状腺癌临床病理参数之间的关系。
作者 姚晓峰 张仑 郑红 金锐 王旭东
机构地区 天津医科大学附属肿瘤医院头颈一科 生化与分子生物学室
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2008年第2期263-263,共1页 Chinese Journal of Experimental Surgery
关键词 癌胚纤维连接蛋白 丝氨酸蛋白酶 甲状腺癌 跨膜 全身恶性肿瘤 临床病理参数 癌旁组织 良性病变
分类号 R736.1 [医药卫生—肿瘤] R373.21 [医药卫生—病原生物学]
  • 相关文献

参考文献2

二级参考文献12

  • 1吕新生.提高甲状腺癌患者的治疗效果及生活质量[J].中国普外基础与临床杂志,2004,11(6):481-482. 被引量：7
  • 2Nicole C, Hodgson, Jaclyn Button, et al. Thyroid Cancer: Is the Incidence Still Increasing? Ann Surgical Onco, 2004, 11 : 1093-1097.
  • 3Clark W, Zhang Z, Chan DW, et al.. The application of clinical proteomics to cancer and other diseases. Clin Chem Lab Med, 2003, 41:1562-1570.
  • 4Jain KK. Role of proteomics in diagnosis of cancer. Technol Cancer Res Treat, 2002, 1:281-286.
  • 5Rai AJ, Chart DW. Cancer proteomica: Serum diagncetica for tumor marker discovery, Ann NY Acad Sci, 2004,1022:286-294.
  • 6Patel PS, Telang SD, Rawal RM, et al. A review of proteomics in cancer research. Asian Pac J Cancer Prev, 2005, 6:113-117.
  • 7Somorjai RL, Dolenko B, Bauragartner R. Class prediction and discovery using gene microarray and proteomics mass spectroscopy data:curses, caveats, cautions. Bioinformatics, 2003, 19 : 1484-1491.
  • 8Furey TS, Cristianini N, Dully N, et al. Support vector machine classification and validation of cancer tissue samples using microarray expression data. Bioinformatics, 2000,16: 903-914.
  • 9Byvatov E, Schneider G. Support vector machine applications in bioinformatics. Appl Bioinformatics, 2003, 2: 67-77.
  • 10Jorissen RN, Gilson MK. Virtual screening of molecular databases using a support vector machine. Chem Inf Model, 2005, 45:549-561.

共引文献15

同被引文献57

  • 1史忠诚,李钰,张贵寅.Ⅱ型跨膜丝氨酸蛋白酶4与肿瘤[J].国外医学（遗传学分册）,2005,28(3):152-155. 被引量：2
  • 2Jtmg H, Lee KP, Park SJ, et al. TMPRSS4 promotes invasion, migration and metastasis of human tumoreells by facilitating an epithelial-mesenchymal transition. Oncogene, 2008, 27: 2635- 2647.
  • 3Stetler-Stevenson WG, Yu AE. Proteases in invasion: matrix metalloproteinases. Semin Cancer Biol, 2001,11 : 143-152.
  • 4Deryugina EI, Quigley JP. Matrix metalloproteinases and tumor metastasis. Cancer Metastasis Rev, 2006,25 : 9-34.
  • 5Hooper JD, Clements JA, Quigley JP, et al. Type II transmembrane serine proteases. Insights into an emerging class of cell surface proteolytic enzymes. J Biol Chem,2001,276 :857-860.
  • 6Wallrapp C, Hahnel S, Muller-PilIasch F, et al. A novel transmembrane serine protease ( TMPRSS3 ) overexpressed in pancreatic cancer. Cancer Res, 2000,60:2602-2606.
  • 7Christiansen JJ, Rajasekaran AK. Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis. Cancer Res,2006,66:8319-8326.
  • 8Kim S, Kang HY, Nam EH, et al. TMPRSS4 induces invasion and epithelial-mesenchymal transition through upregulation of integrin 5 and its sinaling pathways. Carcinogenesis, 2010,31 : 597 -606.
  • 9Hooper JD, Clements JA, Quigley JP, et al. Type II trans- membrane serine proteases: insights into an emerging class of cell surface proteolytic enzymes. J Biol Chem, 2001,276 (2) : 857-860.
  • 10Wallrapp C, Hahnel S, Muller-Pillasch F, et al. A novel transmembrane serine protease (TMPRSS3)overexpressed in pancreatic cancer. Cancer Res, 2000,60 (10) : 2602-2606.

引证文献3

二级引证文献4

中华实验外科杂志
2008年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部