摘要
目的:解决人用布氏菌素的非特异反应问题。方法:用三氯醋酸和硫酸铵从布氏菌菌液中制备了富含蛋白(95%以上)的布氏菌素。结果:经多次动物试验证明,该菌素具有良好的变态反应原性,其特异性和敏感性与参考标准品完全一致。结论:实验研究结果显示,该制品为纯度高、质量好、易标化的新型布氏菌病诊断制剂。
Objective: In order to solve the nonspecific reaction problem of Brucellin for human beings. Methods: We have prepared Brucellin rich in proteins (exceeding ninty five percent)with trichloracetic acid and ammonium sulphate from Brucella cultures. Results: Repeatedly animal experiments proved that these Brucellin have good original metamorphotic reaction.The specificity and sensibility is consistent with the standardized product.Conclusion: The experiment results indicated that the Brucellin is a new type high purity,good quality and easy standardization diagnostic preparation for Brucellosis.
出处
《河南医学研究》
CAS
1997年第4期298-300,共3页
Henan Medical Research
基金
河南省科委资助课题
关键词
布鲁氏菌病
布氏菌素
研制
brucellin
metamorphotic reaction
specificity
sensiblity