正常人与青少年特发性脊柱侧凸患者椎弓根磁共振对比

Comparison of vertebral arch pedicle asymmetry between normal people and patients with adolescent idiopathic scoliosis by magnetic resonance imaging

目的:应用MRI成像技术对正常人与青少年特发性脊柱侧凸(AIS)患者椎弓根的不对称性进行对比分析,评价AIS患者是否表现出一致的形态学特点。方法:分析8位正常人的76个椎弓根和10例AIS早期患者的80个椎弓根的MRI成像。测定并比较正常人和AIS早期患者椎弓根不对称的程度和方向。结果:正常人表现出椎弓长度的不对称,左侧椎弓根和椎板长度较长,差异无统计学意义。AIS患者也表现出不对称,两者相比后者的不对称性更明显并有统计学意义。AIS患者的这种椎弓根不对称在侧凸凸侧和凹侧之间没有一致的分布。结论:研究AIS椎骨形态学的标准应该重新考虑,AIS椎骨形态不对称的类型依赖于特定的病因。

Objective： To assess vertebral arch pedicle asymmetry in normal people and patients with adolescent idiopathic scoliosis in the early stages of scoliosis development and to determine whether patients with adolescent idiopathic scoliosis （AIS） exhibit a consistent vertebral morphology. Methods： The magnetic resonance imagings （MRI） of normal and patients with AIS were measured to obtain parameters including pedicle lengths, pedicle widths, pedicle areas, pedicle perimeters, and lamina lengths. The extent and direction of asymmetry in vertebrae from normal people and patients with were determined and compared. Results： Normal people displayed significant asymmetry in length of vertebral arch, with the left pedi- cle and lamina length being significantly greater. In the patients with AIS, the vertebral arches were also significantly asymmetric. In comparing the extent of asymmetry to the normal people, the patients with AIS showed greater asymmetry. However, this asymmetry did not reach significant levels. Furthermore, there was no consistent distribution of this asymmetry between the convex and the concave sides of the curve. Conclusion： The fact that the greater length in the left pedicle and lamina than those in the right pedicle and lamina in normal patients is significant and strongly, which suggest that the patterns of vertebral morphology in AIS might depend on the specific cause.