辽宁农村地区高血压病人群的血脂水平

Epidemiology of Blood Lipid Level Among Rural Groups with Hypertension in Liaoning Province

目的调查辽宁省农村地区高血压人群血脂水平的流行病学特征,为农村高血压人群血脂异常的防治提供科学依据。方法采用分层整群抽样方法于2004～2006年对辽宁省阜新县农村地区6412名(男性2805名,女性3607名)年龄≥35岁患原发性高血压病的常住人群(≥5年)进行流行病学调查和实验室检查,根据2006中国成人血脂异常防治指南标准,对血脂异常情况进行统计分析。结果(1)在辽宁省阜新农村高血压人群中,女性血脂平均水平高于男性,差异具有显著性(P<0.01)。(2)总胆固醇升高(≥6.21mmol/L),高密度脂蛋白胆固醇减低(<1.03mmol/L),低密度脂蛋白胆固醇升高(≥4.16mmol/L),甘油三酯升高≥(2.26mmol/L)的异常率分别为16.9%,8.8%,4.4%和19.8%。(3)随着血压分级的升高,总胆固醇和高密度脂蛋白胆固醇的异常率增高,差异具有统计学意义(P<0.05),但低密度脂蛋白胆固醇和甘油三酯未表现出这一趋势。结论辽宁省阜新县农村地区高血压病人群中血脂异常更为明显,对这一人群进行积极的干预尤为重要。

Aim To investigate the current epidemiological characteristics of blood lipid levels among rural hypertensive patients in Liaoning province and to provide scientific basis for the prevention and treatment of dyslipoproteinemia.Methods A cross-sectional survey was conducted during 2004～2006,through cluster multistage and random sampling to a resident（≥5 years） groups of 6 412 individuals（2,805 men,3,607 women） aged ≥35 years old with hypertension in the countryside of Liaoning province and blood chemical analyses were performed at a central, certified laboratory so as to understand the prevalence of dyslipoproteinemia based on criteria of the prevention and treatment of dysfipoproteinemia in 2006 in China, SPSS11.5 of statistical software was used for data analysis. Results （1）Theaveragelevelofbloedhpids （TC,HDLC, LDLC and TG）hadhigher levels in hypertensive women than that in hypertensive men （ P 〈 0. 001 ）. （ 2 ） The prevalence of isolated hypereholesterolemia （ TC ≥ 6.21 mmol/L）, low HDLC concentration （HDLC 〈 1.03 mmol/L）, increased LDLC concentration （ LDLC ≥ 4.16 mmol/ L）, isolated hypertriglyceridemia （TG≥2.26 mmol/L） was 16.9%, 8.8%, 4.4%, and 19.8%. （3）The prevalence of TC increased with the increased stage of blood pressure and it showed a significant difference among 3 stages. In contrast, the prevalence of HDLC decreased with the increased stage of blood pressure and it was also significant （ P 〈 0.05 ） ; however, we didn＇ t see a trend between LDLC and the stage of blood pressure and TG and the stage of blood pressure. Conclusion The prevalence of dyslipidemia was relatively high among rural hypertensive patients in Liaoning province, it is very important to prevent and control dyslipidemia for us.