实验用五指山小型猪正常生理值测定

Determination of Clinical Normal Physiological Parameters in Chinese Wuzhishan Pig

目的建立中国实验用五指山小型猪正常生理参考值。方法选用24头中国实验用五指山小型猪,雌雄各半,对其体重、体温2、0项血液学指标2、1项血清生化指标、4项心电图指标、尿常规、主要脏器重量和脏器系数进行了测定,并选用同一批动物对其血液学、血清生化、心电图等生理指标进行了为期4个月的连续测定。结果五指山小型猪部分指标如血液学的WBC、LYM%、GRAN%、PCT,血清生化指标如ALP、P、Na、Cl雌雄动物相差显著,其他指标较一致。心电图指标、体重、主要脏器系数雌雄较一致,部分生化指标如GGT等与临床人正常值较接近。动态测定结果提示各项主要指标测定结果较稳定,随着饲养时间的延长,少数血液生化指标如WBC、GOT有一定的改变,但幅度较小。结论初步建立了中国实验用五指山小型猪正常生理参考值,这些生理数据的采集为其进一步开发和应用提供了有益的参考。

Objective To obtain the reference normal physiological parameters of Wuzhishan pig（WZSP）. Methods The normal physiological parameters of 24 WZSPs, male and female in half, were detemined and compared with different sexes,including body weight, body temperature, 20 normal values of hematology, 21 normal values of biochemistry, 4 normal values of cardiograph, urine, organ weight and organ relative weight. Part of parameters were detemined continuously for 4 months. Results The results showed that there were no significant between male and female except some hematological parameters such as WBC, LYM%, GRAN%, PCT and biochemistry such as ALP, P, Na, C1. Some values of biochemistry such as GGT were in conformity to those of human. The four-month continuous determination showed most physiological parameters were stable. Conchlsion The normal ranges of physiological parameters of WZSP were therefore established and these data may give a useful reference for further studies and use of WZSP in medical field.