西宁地区居民骨质疏松症的调查分析(附293例X线片掌骨指数分析)

Investigation of Residents’ Osteoporosis in Xining Area ——Analysis of 293 Metacarpal Bone Indexes on X-ray Film

目的:调查青海西宁地区掌骨指数(IND)与骨质密度(BMD)变化规律,为该地区骨质疏松症(osteoporosis,OP)的预防和治疗提供流行病学依据。方法:用测量人体第二掌骨指数(IND)形态学的方法测量骨质密度,采用"中国人原发性骨质疏松症诊断标准"(试用)。结果:IND在2岁～与15岁～IND值比较,差别有统计学意义(P<0.05),与60岁～以后比较,差别无统计学意义(P>0.05);IND在40岁～与65岁～比较,差别有统计学意义(P<0.05);25岁～至30岁～IND值达峰值0.60±0.14;45岁～BMD开始降低,到60岁～以后明显降低。结论:①西宁地区IND减少的时间和速度与年龄增长、高原居民生活方式有关;②45岁～及60岁～以后是OP的好发年龄段,45岁以前应该预防OP的发生。

Objective：To investigate the changes on osteoporosis sickness of residents in Xining area to protect and treat it. Methods：The ossein density （BMD） was examined by the second metacarpal bone index （IND） on X--ray film using ＂the Chinese primary osteoporosis sickness diagnosis standard＂ （test）. Results： There was a significant difference of IND （P〈0. 05） between 2- and 15-IND level, as well between 40-and 65-IND（P〈0.05）. No difference（P〉0. 05） between 2- and 60-later. 45-BMD had a reduce when the 25- to the 30-IND reach to the peak value 0. 60±0. 14 and significant decreased after 60 -later. Conclusions： （1）decreased IND level on time and speed correlated with residents＇ age grow and their life style in Xining area. （2） 45- and 60-later will be a good age of OP, so we should prevent OP occurrence before 45 years old.