对我院抗菌药物连续3年应用状况的调查分析

Use of Antibiotics in Our Hospital in Three Consecutive Years:Survey and Analysis

目的：了解我院抗菌药物应用状况,为正确调控抗菌药物供应结构、制定监管制度、促进合理应用提供决策依据。方法：通过医院信息管理系统,分别调取我院门诊药房和住院药房2005年2、006年2、007年连续3年1月～6月抗菌药物的使用数量及金额,以用药金额百分率、用药频度百分比为评价指标。结果：连续3年抗菌药物占总用药金额的比例已接近30%,高于全国24.18%平均水平,处于二级综合医院指标的高限（≤30%）;头孢类应用日益广泛,青霉素类呈走低趋势,氨基糖苷类、大环内酯类用量相对较稳定,硝基咪唑类稳中有升,喹诺酮类用量逐年降低且同类品种的更新率较高;抗菌药物使用品种更新过快,缺乏相对固定性。结论：抗菌药物合理应用监管工作亟待加强。

OBJECTIVE：To probe into the application status of antibiotics in our hospital so as to provide basis for the decision making in regulating supply structure of antibiotics,constituting control system and promoting reasonable drug use.METHODS：Data about the consumption quantity and consumption sum of the antibiotics in outpatient and inpatient dispensaries during the upper half years of 2005,2006 and 2007 retrieved from HIS（the hospital information system） were analyzed with percentages of consumption sum and DDDs as indexes.RESULTS：The proportion of the antibiotics in the three consecutive years has approached to 30% of the total in terms of consumption sum,higher than the national average level of 24.18% or at the top limit（≤30%） of second grade general hospital.Cephalosporins were used widely,but penicillins showed downward trend;the use of aminoglycosides and macrolides remained stable comparatively.The consumption of nitroimidazoles increased steadily,while that of quinolones decreased year by year,which showed high refresh rate for the same category.The categories of antibiotics refreshed too quickly thus lacking relative stability.CONCLUSION：It is urgent to tighten control on the rational use of antibiotics.