过敏性紫癜与幽门螺杆菌感染的临床相关性初步探讨

Exploring the clinical relationship between Henoch-Schnlein purpura and Helicobacter pylori infection

目的 研究幽门螺杆菌感染与过敏性紫癜的临床关系并指导治疗。方法 对93例过敏性紫癜患者进行幽门螺杆菌检测，对合并HP感染者在常规治疗基础上进行HP根治并观察其临床疗效。结果 93例过敏性紫癜中有41例合并HP感染44．09。％，同时行HP根治后过敏性紫癜临床症状迅速消退，恢复快、复发率低，随访2个月～2年效果好。结论 HP感染可能是HSP发病的重要因素之一，根治HP有利HSP的治疗康复。

Objective To study the clinical relationship between Henoch-Schnlein purpura and Helicobacter pylori infection and direct therapy. Method Helicobacter pylori （Hp） was detected in 93 cases with Henoch-Schnlein purpura, and then the Hp-positive patients were treated with routine treatment accompanied with Hp eradication therapy. Result The Hp-positive rate was 44.09% in patients with Henoch-Schnlein purpura. The symptoms of Henoch-Schnlein purpura disappeared rapidly and recurred few after routine treatment combined with eradication therapy to against Hp. Conclusion Helicobacter pylori infection maybe one of important causes in Henoch-Schnlein purpura. Eradication therapy in Hp-positive patients may be better for treatment and recovery.