鼻息肉预后与病理分型相关性分析

The relation of prognosis with pathological types on the nasal polyp

目的探讨鼻息肉的不同组织病理学表现在鼻息肉中的表达程度与手术疗效的相关性。方法选取鼻息肉患者40例(58侧,两侧病变以病重侧计);均行鼻内窥镜鼻息肉摘除及窦口开放术。术中所取息肉组织立即浸泡于10%中性甲醛液中,石蜡包埋后连续切2片,片厚5μm。取1片行HE染色并在光镜下观察,根据显微镜下所见将鼻息肉分为4型:腺体型、血管型、纤维型、混和型。应用Spearman软件进行秩相关统计学分析,P<0.05具有统计学意义。结果术后随访6个月,根据1997年海口鼻科会议制定的疗效评定标准进行评定,Ⅰ期愈合22例(22/4055%),延期愈合8例(8/4020%),好转6例(6/4015%),复发4例(4/4010%)。结论鼻息肉组织病理学分类与鼻息肉的预后无明显相关性,但有正相关趋势。

Objective To study the relation between nasal polyp pathology in nasal polyps and the effect of surgery. Methods Select 40 cases（58 sides） of nasal polyp were selected from March 2005 - September 2005 in my hospital. All the cases had the nasal polyp removed surgery and the sinuses opened surgery in endoscopy. The nasal polyps was soaked in 10% neutral formalelehyde immediately. The pathological sections was maked and HE staining. Nasal polyps was divided four types： （1） glandness type; （2） blood vessal type; （3）fibrin type; （4） mixness type. Analyses were performed with Spearman. Results The results shown that early recover 22 cases; Postponed recover 8 cases; Clinical mend 6 cases; Recrudescence 4 cases after six monthes. Conclusion The nasal polyp pathology is not relativity with the response to surgery.